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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha : |
20/03/2024 |
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Actualizado : |
20/03/2024 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Autor : |
MACÊDO, I.L. DE; SOUSA, D.E.R. DE; SOUZA, A.D.R.; ARMIÉN, A.G.; MACHADO, M.; CASTRO, M.B. DE |
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Afiliación : |
ISABEL LUANA DE MACÊDO, Veterinary Pathology and Forensic Laboratory, Veterinary Teaching Hospital, University of Brasilia, Distrito Federal, Brazil; Graduate Program in Animal Science, University of Brasilia, Distrito Federal, Brazil; DAVI EMANUEL RIBEIRO DE SOUSA, Veterinary Pathology and Forensic Laboratory, Veterinary Teaching Hospital, University of Brasilia, Distrito Federal, Brazil; Graduate Program in Animal Science, University of Brasilia, Distrito Federal, Brazil; ANTONIZETE DOS REIS SOUZA, Primatology Center, Fazenda Água Limpa, University of Brasilia, Distrito Federal, Brazil; ANÍBAL G. ARMIÉN, California Animal Health & Food Safety Laboratory System (CAHFS), School of Veterinary Medicine, University of California, Davis, USA; MIZAEL MACHADO DA COSTA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; MÁRCIO BOTELHO DE CASTRO, Veterinary Pathology and Forensic Laboratory, Veterinary Teaching Hospital, University of Brasilia, Distrito Federal, Brazil; Graduate Program in Animal Science, University of Brasilia, Distrito Federal, Brazil. |
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Título : |
Fatal Africanized bee attack in captive non-human primates (Saimiri ustus and Sapajus libidinosus). |
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Complemento del título : |
Short communication. |
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Fecha de publicación : |
2024 |
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Fuente / Imprenta : |
Toxicon. 2024, Volume 241, Article 107666. https://doi.org/10.1016/j.toxicon.2024.107666 |
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ISSN : |
0041-0101 |
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DOI : |
10.1016/j.toxicon.2024.107666 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 8 February 2024, Revised 26 February 2024, Accepted 27 February 2024, Available online 28 February 2024, Version of Record 8 March 2024. -- Correspondence: Castro, M.B.D.; Veterinary Pathology and Forensic Laboratory, Veterinary Teaching Hospital, University of Brasilia, Distrito Federal, Brazil; email:mbcastro@unb.br --Funding: This research was partly financed by the Coordination for the Improvement of Higher Education Personnel - Brazil (CAPES) - Finance Code 001 (ILM, DERS). We thank the National Council for Scientific and Technological Development ( CNPq ) for the Research Productivity grant (PQ), process n. 307909/2021-2 (MBC). |
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Contenido : |
ABSTRACT.- Bee stings (BS) are a life-threatening issue and a growing concern for public health and animals in the Americas. We describe the clinical, pathological, and ultrastructural findings of a massive lethal bee attack in two non-human primates (NHPs). Both animals showed BS scattered throughout the skin, surrounded by a local reaction, diffuse pulmonary congestion, edema, hemorrhage, and remarkable degeneration and necrosis of renal epithelial cells from the proximal and distal tubules, characterizing a systemic bee envenomation reaction. © 2024 Elsevier Ltd |
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Palabras claves : |
Bee venom; Envenomation; Kidney injury; Macaques; PLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA; Systemic reaction. |
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Asunto categoría : |
L40 Estructura animal |
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Marc : |
LEADER 02135naa a2200289 a 4500
001 1064505
005 2024-03-20
008 2024 bl uuuu u00u1 u #d
022 $a0041-0101
024 7 $a10.1016/j.toxicon.2024.107666$2DOI
100 1 $aMACÊDO, I.L. DE
245 $aFatal Africanized bee attack in captive non-human primates (Saimiri ustus and Sapajus libidinosus).$h[electronic resource]
260 $c2024
500 $aArticle history: Received 8 February 2024, Revised 26 February 2024, Accepted 27 February 2024, Available online 28 February 2024, Version of Record 8 March 2024. -- Correspondence: Castro, M.B.D.; Veterinary Pathology and Forensic Laboratory, Veterinary Teaching Hospital, University of Brasilia, Distrito Federal, Brazil; email:mbcastro@unb.br --Funding: This research was partly financed by the Coordination for the Improvement of Higher Education Personnel - Brazil (CAPES) - Finance Code 001 (ILM, DERS). We thank the National Council for Scientific and Technological Development ( CNPq ) for the Research Productivity grant (PQ), process n. 307909/2021-2 (MBC).
520 $aABSTRACT.- Bee stings (BS) are a life-threatening issue and a growing concern for public health and animals in the Americas. We describe the clinical, pathological, and ultrastructural findings of a massive lethal bee attack in two non-human primates (NHPs). Both animals showed BS scattered throughout the skin, surrounded by a local reaction, diffuse pulmonary congestion, edema, hemorrhage, and remarkable degeneration and necrosis of renal epithelial cells from the proximal and distal tubules, characterizing a systemic bee envenomation reaction. © 2024 Elsevier Ltd
653 $aBee venom
653 $aEnvenomation
653 $aKidney injury
653 $aMacaques
653 $aPLATAFORMA DE INVESTIGACIÓN EN SALUD ANIMAL - INIA
653 $aSystemic reaction
700 1 $aSOUSA, D.E.R. DE
700 1 $aSOUZA, A.D.R.
700 1 $aARMIÉN, A.G.
700 1 $aMACHADO, M.
700 1 $aCASTRO, M.B. DE
773 $tToxicon. 2024, Volume 241, Article 107666. https://doi.org/10.1016/j.toxicon.2024.107666
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Registro original : |
INIA Las Brujas (LB) |
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Registro completo
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Biblioteca (s) : |
INIA Las Brujas. |
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Fecha actual : |
25/06/2021 |
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Actualizado : |
25/06/2021 |
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Tipo de producción científica : |
Artículos en Revistas Indexadas Internacionales |
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Circulación / Nivel : |
Internacional - -- |
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Autor : |
FEDERICI, M.; ARTIGAS, R.; GUERRA, S.; BRANDA, A.; VÁZQUEZ, N.; NICOLINI, P.; DUTRA, F.; LLAMBÍ, S. |
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Afiliación : |
MARIA TERESA FEDERICI RODRIGUEZ, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; RODY ARTIGAS, Facultad de Veterinaria, Universidad de la República (UDELAR), Montevideo, Uruguay; SOFÍA GUERRA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; ANDREA BRANDA SICA, INIA (Instituto Nacional de Investigación Agropecuaria), Uruguay; NOELIA VÁZQUEZ, Facultad de Veterinaria, Universidad de la República (UDELAR), Montevideo, Uruguay.; PAULA NICOLINI, Instituto Superior de la Carne, Universidad de la República (UDELAR), Tacuarembó, Uruguay.; FERNANDO DUTRA QUINTELA, División Laboratorios Veterinarios (DILAVE), Ministerio de Agricultura y Pesca (MGAP), Treinta y Tres, Uruguay.; SILVIA LLAMBÍ, Facultad de Veterinaria, Universidad de la República (UDELAR), Montevideo, Uruguay. |
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Título : |
Detection of the Brachyspina mutation in Uruguayan Holstein cows using real time PCR and melting curve analysis. [Detecção da mutação da Brachyspina em vacas Holandês Uruguaias usando PCR em tempo real e análise da curva de fusão.] |
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Fecha de publicación : |
2021 |
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Fuente / Imprenta : |
Ciencia Rural, 2021, volume 51 (9), Article e20200872. OPEN ACCESS. Doi: https://doi.org/10.1590/0103-8478cr20200872 |
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ISSN : |
1678-4596 (online) |
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DOI : |
10.1590/0103-8478cr20200872 |
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Idioma : |
Inglés |
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Notas : |
Article history: Received 17 Sept 2020; Accepted 05 Jan 2021; Reviewed 07 Mar 2021; Publication in this collection 02 June 2021; Date of issue 2021. |
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Contenido : |
ABSTRACT - Brachyspina syndrome (BS) is a rare monogenic autosomal recessive hereditary disorder of the Holstein Fresian breed caused by a deletion of 3.3Kb in the Fanconi anemia complementation group I (FANCI) gene on BTA-21, which leads to a frame-shift and premature stop codon. Some of the consequences of BS are the reduction of the fertility rate and milk production. This study developed a simple, sensitive, rapid cost- effective assay method based on real time PCR and melting curve analysis for the detection of BS carrier animals. Sixty-eight normal homozygous and four heterozygous carrier genotypes were detected and confirmed through traditional PCR- electrophoresis analysis. We concluded that the assay we have developed proved to be a reliable, highly precise and low-cost tool, which could be used to monitor the presence of the BS mutation in uruguayan Holstein breed.
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RESUMO - A síndrome de Brachyspina (BS) é um defeito hereditário monogênico autossômico recessivo raro da raça Holstein Friesian causado por uma exclusão de 3,3 KB no gene FANCI localizado no cromossomo bovino 21, o que leva a um deslocamento de quadro e um códon de parada prematuro. Uma consequência da BS é a eficiência de reprodução reduzida e a produção de leite. O objetivo deste estudo foi o desenvolvimento de um método simples, rápido e sensível, baseado em PCR em tempo real e análise da curva de fusão para identificar animais portadores de BS. Sessenta e oito genótipos homozigotos normais e quatro heterozigotos foram detectados e confirmados através da análise tradicional de PCR e electophorese. Concluímos que o novo método é uma ferramenta confiável, altamente precisa e de baixo custo, que poderia ser usado para monitorar a presença da mutação BS na raça Holandês uruguaia. MenosABSTRACT - Brachyspina syndrome (BS) is a rare monogenic autosomal recessive hereditary disorder of the Holstein Fresian breed caused by a deletion of 3.3Kb in the Fanconi anemia complementation group I (FANCI) gene on BTA-21, which leads to a frame-shift and premature stop codon. Some of the consequences of BS are the reduction of the fertility rate and milk production. This study developed a simple, sensitive, rapid cost- effective assay method based on real time PCR and melting curve analysis for the detection of BS carrier animals. Sixty-eight normal homozygous and four heterozygous carrier genotypes were detected and confirmed through traditional PCR- electrophoresis analysis. We concluded that the assay we have developed proved to be a reliable, highly precise and low-cost tool, which could be used to monitor the presence of the BS mutation in uruguayan Holstein breed.
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RESUMO - A síndrome de Brachyspina (BS) é um defeito hereditário monogênico autossômico recessivo raro da raça Holstein Friesian causado por uma exclusão de 3,3 KB no gene FANCI localizado no cromossomo bovino 21, o que leva a um deslocamento de quadro e um códon de parada prematuro. Uma consequência da BS é a eficiência de reprodução reduzida e a produção de leite. O objetivo deste estudo foi o desenvolvimento de um método simples, rápido e sensível, baseado em PCR em tempo real e análise da curva de fusão para identificar animais portadores de BS. Sessenta e oito genótipos homozigo... Presentar Todo |
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Palabras claves : |
Análise da curva de fusão; Bos taurus; Brachyspina syndrome; Holandês; Holstein; Melting curve analysis; PCR em tempo real; Real time PCR; Sindrome de Brachyspina. |
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Asunto categoría : |
L10 Genética y mejoramiento animal |
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URL : |
https://www.scielo.br/j/cr/a/kTxvzMF47Cqdb7TbPKHjxxc/?lang=en&format=pdf
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Marc : |
LEADER 03178naa a2200349 a 4500
001 1062156
005 2021-06-25
008 2021 bl uuuu u00u1 u #d
022 $a1678-4596 (online)
024 7 $a10.1590/0103-8478cr20200872$2DOI
100 1 $aFEDERICI, M.
245 $aDetection of the Brachyspina mutation in Uruguayan Holstein cows using real time PCR and melting curve analysis. [Detecção da mutação da Brachyspina em vacas Holandês Uruguaias usando PCR em tempo real e análise da curva de fusão.]$h[electronic resource]
260 $c2021
500 $aArticle history: Received 17 Sept 2020; Accepted 05 Jan 2021; Reviewed 07 Mar 2021; Publication in this collection 02 June 2021; Date of issue 2021.
520 $aABSTRACT - Brachyspina syndrome (BS) is a rare monogenic autosomal recessive hereditary disorder of the Holstein Fresian breed caused by a deletion of 3.3Kb in the Fanconi anemia complementation group I (FANCI) gene on BTA-21, which leads to a frame-shift and premature stop codon. Some of the consequences of BS are the reduction of the fertility rate and milk production. This study developed a simple, sensitive, rapid cost- effective assay method based on real time PCR and melting curve analysis for the detection of BS carrier animals. Sixty-eight normal homozygous and four heterozygous carrier genotypes were detected and confirmed through traditional PCR- electrophoresis analysis. We concluded that the assay we have developed proved to be a reliable, highly precise and low-cost tool, which could be used to monitor the presence of the BS mutation in uruguayan Holstein breed. .-.-.-.-.-.-.-.-.-.- RESUMO - A síndrome de Brachyspina (BS) é um defeito hereditário monogênico autossômico recessivo raro da raça Holstein Friesian causado por uma exclusão de 3,3 KB no gene FANCI localizado no cromossomo bovino 21, o que leva a um deslocamento de quadro e um códon de parada prematuro. Uma consequência da BS é a eficiência de reprodução reduzida e a produção de leite. O objetivo deste estudo foi o desenvolvimento de um método simples, rápido e sensível, baseado em PCR em tempo real e análise da curva de fusão para identificar animais portadores de BS. Sessenta e oito genótipos homozigotos normais e quatro heterozigotos foram detectados e confirmados através da análise tradicional de PCR e electophorese. Concluímos que o novo método é uma ferramenta confiável, altamente precisa e de baixo custo, que poderia ser usado para monitorar a presença da mutação BS na raça Holandês uruguaia.
653 $aAnálise da curva de fusão
653 $aBos taurus
653 $aBrachyspina syndrome
653 $aHolandês
653 $aHolstein
653 $aMelting curve analysis
653 $aPCR em tempo real
653 $aReal time PCR
653 $aSindrome de Brachyspina
700 1 $aARTIGAS, R.
700 1 $aGUERRA, S.
700 1 $aBRANDA, A.
700 1 $aVÁZQUEZ, N.
700 1 $aNICOLINI, P.
700 1 $aDUTRA, F.
700 1 $aLLAMBÍ, S.
773 $tCiencia Rural, 2021, volume 51 (9), Article e20200872. OPEN ACCESS. Doi: https://doi.org/10.1590/0103-8478cr20200872
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